Differential Diagnosis for Narcolepsy

This activity is part of a series

Faculty

Richard K. Bogan, MD, FCCP, FAASM
Associate Clinical Professor
University of South Carolina Medical School
Columbia, SC
Medical University of South Carolina
Charleston, SC
Principal, Bogan Sleep Consultants, LLC
Columbia, SC
Richard K. Bogan, MD, FCCP, FAASM

Dr. Bogan is the President of Bogan Sleep Consultants, LLC. He is also Associate Clinical Professor at the University of South Carolina School of Medicine and Associate Clinical Professor at the Medical University of South Carolina in Charleston, SC.

Dr. Bogan received his bachelor’s degree in chemistry from Wofford College and his MD degree from the Medical University of South Carolina in Charleston. He served his internship and residency, as well as Chief Medical Resident, at the University of Alabama Hospital and Clinics in Birmingham. Thereafter, he completed a fellowship and assistant professorship in the Pulmonary Division of the Department of Medicine at the University of Alabama School of Medicine. He has been certified by the American boards of Sleep Medicine, Internal Medicine, and Pulmonary Diseases.

Dr. Bogan has served as principal investigator on numerous clinical trials in the past and continues to do so now. He has a variety of publications and research interests that focus on topics such as narcolepsy, insomnia, sleep apnea, shift work sleep disorder, restless legs syndrome/periodic limb movement disorder, chronic fatigue/fibromyalgia, and circadian rhythm abnormality.

Michael J. Thorpy, MD
Professor of Neurology, Albert Einstein College of Medicine
Director, Sleep-Wake Disorders Center, Department of Neurology
Montefiore Medical Center, Bronx, NY
President, New York State Society of Sleep Medicine
Past President, Sleep Section of the Academy of Neurology
Michael J. Thorpy, MD

Dr. Thorpy is a Professor of Neurology at Albert Einstein College of Medicine and Director of the Sleep-Wake Disorders Center in the Department of Neurology at Montefiore Medical Center, both in New York. In addition to treating patients with sleep disorders, he conducts research in narcolepsy, insomnia, and sleep apnea. He is President of the New York State Society of Sleep Medicine, Past President of the Sleep Section of the Academy of Neurology, and Past Secretary of the National Sleep Foundation. In 1993 Dr. Thorpy received the Nathaniel Kleitman Award from the American Academy of Sleep Medicine, one of the field’s highest honors, and in 2012 he received the Lifetime Achievement Award from the National Sleep Foundation.

Born in New Zealand, Dr. Thorpy earned his medical degree from the University of Otago Medical School. After receiving postgraduate training in Dunedin, New Zealand; Bombay, India; and London, England, he completed his residency in neurology at the State University of New York in Syracuse and a neuroendocrinology fellowship at Albert Einstein College of Medicine and Montefiore Medical Center. Dr. Thorpy is board certified in sleep medicine.

He has published extensively on narcolepsy, insomnia, and sleep disorders. He chaired the first International Classification of Sleep Disorders and has published more than 250 peer-reviewed articles and chapters, including publications in journals such as The New England Journal of Medicine. His numerous books include The Encyclopedia of Sleep and Sleep Disorders, Parasomnias (2010), Sleepiness (2011), Neuroimaging of Sleep and Sleep Disorders (2012), Genetics of Sleep and Sleep Disorders (2013), Narcolepsy: a Clinical Guide (2016), and SleepMultiMedia, The Computerized Textbook of Sleep Medicine (v12).0 (2023).

Dr. Thorpy has given more than 100 television, radio, and print interviews on sleep disorders.

Statement of Need

The road to diagnosis of narcolepsy is long, in many cases taking over 10 years. Many symptoms, specifically excessive daytime sleepiness (EDS), may overlap with not only other sleep disorders, but also related comorbidities, and can confound differential diagnosis. Additionally, the diagnosis process can be complicated, and diagnostic tools may be difficult to interpret. Effective education is necessary for clinicians to identify and differentiate narcolepsy from other disorders, properly utilize and interpret diagnostic tools, and recognize when to refer patients to a sleep specialist for clinicians not specialized in sleep.

The second episode of this CMEO BriefCase series on narcolepsy focuses on distinguishing narcolepsy from other disorders, with expert faculty demonstrating how to choose, implement, and interpret screening and diagnostic tools.

Learning Objective

Use appropriate diagnostic tools to differentiate narcolepsy from EDS associated with other medical and psychiatric disorders.

Financial Support

This program is supported by an independent medical education grant from Jazz Pharmaceuticals.

Target Audience

Sleep specialists, primary care practitioners, pulmonologists, neurologists, psychiatrists, physician associates (PAs), nurse practitioners (NPs), nurses, and pharmacists

Credit Information

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Activity UAN: JA0007185-0000-23-093-H01-P

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Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process.

Dr. Bogan reports the following financial relationships:

Consultant: Avadel; Axsome Therapeutics, Inc.; Harmony Biosciences; Jazz Pharmaceuticals, Inc.; Oventus; and Takeda Pharmaceuticals U.S.A., Inc.

Research Support: Apnimed; Avadel; Bayer; Bresotec Medical; Eisai Inc.; Fisher Paykel Healthcare; FRESCA Medical; Idorsia Pharmaceuticals US Inc.; Jazz Pharmaceuticals, Inc.; LivaNova; Merck & Co., Inc.; NLS Pharmaceutics; Philips; Roche; Sanofi; Sommetrics, Inc.; Suven Pharma; Takeda Pharmaceuticals U.S.A., Inc.; and Vanda Pharmaceuticals Inc.

Speakers Bureau: Eisai Inc.; Harmony Biosciences; Idorsia Pharmaceuticals US Inc.; and Jazz Pharmaceuticals, Inc.

Dr. Thorpy reports the following financial relationships:

Advisory Board/Consultant: Alkermes; Axsome Therapeutics, Inc.; Balance Therapeutics; Eisai Inc.; Flamel Technologies/Avadel; Harmony Biosciences; Idorsia Pharmaceuticals Ltd; Jazz Pharmaceuticals, Inc.; NLS Pharmaceutics; Suven Life Sciences Ltd.; Takeda Pharmaceuticals U.S.A., Inc..; and XWPharma Ltd.

Disclosures were obtained from the following peer reviewer and CME Outfitters, LLC, staff, with no disclosures to report:

  • Christina Rivera Carpenter, PhD, RN (peer reviewer)
  • Evan Luberger (planning committee)
  • Meghann Taft-Lockard (planning committee)
  • John Jones, PharmD (planning committee)
  • Susan H. Yarbrough, CHCP (planning committee)
  • Sandra Caballero, PharmD (planning committee)
  • Sharon Tordoff (planning committee)

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

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BC-101-080423-43

Differential Diagnosis for Narcolepsy
Event Date: 08/04/2023 at 4:00 am EST