How to Treat ARIA in Emergency Settings: Timely Communication with Multi-Disciplinary Colleagues

Launch Date

12/21/2023 at 5:00 am EST

Credit Amount

0.5

Credit Expires

12/21/2024

This activity is part of a series

Faculty

Nicolas Villain, MD, PhD

Associate Professor of Neurology

Sorbonne University

Institute of Memory and Alzheimer’s Disease

Department of Neurology

Pitié-Salpêtrière Hospital

Assistance Publique – Hôpitaux de Paris

Paris, France

Karen Greenberg, DO, DO, FACOEP-D, FAAEM, FAHA

Global Neurosciences Institute

Assistant Professor of Neurosurgery, Drexel University College of Medicine

Clinical Assistant Professor (Adjunct) of Neurology, Lewis Katz School of Medicine at Temple University

Assistant Professor of Emergency Medicine, Drexel University College of Medicine

Clinical Assistant Professor of Emergency Medicine, Philadelphia College of Osteopathic Medicine

Philadelphia, PA

Clinical Assistant Professor of Emergency Medicine, Rowan University School of Osteopathic Medicine

Stratford, NJ

Statement of Need

Given the novelty of amyloid-targeting treatments (ATTs) for Alzheimer’s disease, health care professionals specializing in emergency medicine are unfamiliar with best practices for managing patients receiving ATTs who present to emergency settings with symptoms of amyloid-related imaging abnormalities (ARIA). These clinicians need to be aware of the best ARIA management guidance for supportive care, be able to interpret clinical trial protocols for management of serious ARIA events, provide tools and resources to patients, have experience with patient case examples in order to individualize treatment, and communicate with multidisciplinary colleagues about current evidence and best management practices.

The third and final episode of this CMEO BriefCase series focuses on a case involving a patient on an ATT presenting to the emergency department (ED), highlighting ED protocols to streamline care for patients with severe ARIA, recommendations for treatment and supportive care measures, global resources for guidance as the ATT landscape expands, management of ARIA according to best guidance, and communication with ATT-treating clinicians and radiologists.

Learning Objective

Manage ARIA in patients receiving ATTs according to best guidance, including communication with ATT treating clinicians and radiologists

Financial Support

This activity is supported by an educational grant from Lilly.

Target Audience

Health care providers, on a global level, who are involved in emergency medicine: Physicians, nurse practitioners (NPs), physician associates (PAs), nurses, triage specialists, and pharmacists

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Interprofessional (IPCE) 0.5

This activity was planned by and for the healthcare team, and learners will receive 0.50 Interprofessional Continuing Education Credit for learning and change.

Physicians (ACCME) 0.5

CME Outfitters, LLC, designates this Enduring Material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses (ANCC) 0.5

This activity is designated for 0.50 contact hours.

California Residents: This continuing nursing education activity was approved by the California Board of Registered Nursing. CME Outfitters LLC’s provider number is CEP15510.

Pharmacists (ACPE) 0.5

This application-based activity is approved for 0.50 contact hours ( 0.05 CEUs) of continuing pharmacy credit ( JA0007185-0000-23-132-H01-P ).

PAs (AAPA) 0.5

CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.50 AAPA Category 1 CME credits. Approval is valid until 12/21/2024. PAs should only claim credit commensurate with the extent of their participation.

ABIM MOC 0.5

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 medical knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

MIPS Improvement Activity

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

Royal College MOC

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UEMS-EACCME®

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Disclosure Declaration

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process.

Dr. Villain reports the following financial relationships:

Grants: Travel grant from GE Healthcare SAS; Merz-Pharma; and UCB Pharma GmbH

Dr. Greenberg reports the following financial relationships:

Speakers Bureau: Genentech, Inc. (ended 12/31/21)

Other financial or material support: Unpaid local principal investigator or sub-investigator for Alector, Inc.; Biogen; Eisai Inc.; Eli Lilly and Company; Janssen Global Services, LLC/Johnson & Johnson; Novo Nordisk A/S; Roche; and UCB Pharma. Unpaid national coordinator for AB Science and ADvantage Therapeutics GmbH.
Unpaid lecturer in symposia organized by Eisai Inc. and the Servier Foundation.

Disclosures were obtained from the following peer reviewer and CME Outfitters, LLC, staff, with no disclosures to report:

Marlon (Tony) Graham, MD (peer reviewer)
Elizabeth Naber, MSN, RN, CCRN-K, CNRN, TCRN (peer reviewer)
Susan Perry (planning committee)
Erin Spencer (planning committee)
Susan H. Yarbrough, CHCP (planning committee)
Sandra Caballero, PharmD (planning committee)
Sharon Tordoff (planning committee)

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

Obtaining Credit

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