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In this CME Outfitters livestream symposium, faculty will examine how pro-inflammatory cytokines drive inflammation in the pathogenesis of IBD, explore the role of the IL-23/Th17 inflammatory axis in IBD pathogenesis, and discuss the clinical implications of anti–IL-23 agents used in the treatment of IBD to bind to CD64 receptors on IL-23–producing cells.
Miguel Regueiro earned his bachelor’s degree at the University of Pennsylvania, his medical degree at Drexel (Hahnemann) University and completed his internal medicine internship, residency, and clinical and research fellowship training in gastroenterology at Harvard Medical School’s Beth Israel Hospital.
Dr. Regueiro was Professor of Medicine and Clinical and Translational Science at the University of Pittsburgh School of Medicine from 2000 to 2018. There he served as the IBD Clinical Medical Director, Senior Medical Lead of Specialty Medical Homes, was Professor with Tenure, and honored as the UPMC Endowed Chair for Patient Centered Care in Inflammatory Bowel Diseases.
Dr. Regueiro is currently the Chair of the Department of Gastroenterology and Hepatology and Chair of the Digestive Disease and Surgery Institute at Cleveland Clinic in Ohio. He serves as Medical Co- Chair of Digestive Disease and Surgical Institute Research Governance committee and is Professor of Medicine at the Lerner College of Medicine, Cleveland Clinic.
Dr. Regueiro’s main clinical and research interest is Inflammatory Bowel Diseases with a focus on the natural course of these diseases and postoperative prevention of Crohn’s disease. Recently, he has been involved in transformative medicine initiatives and developing new models of healthcare, including the first-of-its kind specialty medical home for IBD. Dr. Regueiro is investigating alternative models of care in population-based health that integrates patients, payers, providers, pharmaceutical industry, and other facets of healthcare delivery around these novel programs.
In this CME Outfitters live chapter meeting, expert faculty will discuss important strategies for identifying how to best overcome delays in insulin initiation as well as how to differentiate current and emerging basal insulin therapies and their impact on therapeutic inertia.
In this CME Outfitters livestream symposium, faculty will discuss the integration of guideline-based universal testing to address screening gaps for HIV, HBV, and HCV; evaluate pan-viral testing strategies that improve engagement in diverse practice settings; and explore strategies to incorporate guideline-recommended pan-viral and perinatal screenings into the care of patients who are pregnant to improve outcomes and limit perinatal transmission.
In this CME Outfitters livestream symposium, expert faculty will discuss the disease burden and impact of LGS on QoL for patients and caregivers, the utilization of diagnostic criteria and distinguishing features of both early- and late-onset LGS to achieve early and accurate diagnosis, and strategies to optimize LGS management across the lifespan of these patients.
Dr. Dixon-Salazar is a neuroscientist, geneticist, and patient advocate. Her desire to get her PhD was inspired by her daughter who developed Lennox-Gastaut Syndrome (LGS) at the age of 2. She completed her PhD and postdoctoral work at UC, San Diego, where she studied the mechanisms of brain development and synaptic plasticity, identified genetic causes of rare disorders in children, and researched precision therapeutics in stem cell and animal models of pediatric disease. During her research tenure, and after 16 years of watching daily, unrelenting seizures in her child, she uncovered the driver of her daughter’s illness and identified a novel precision therapy that improved her child’s life.
Dr. Dixon-Salazar left academia after 15 years in the lab with a drive to decrease the amount of time it would take for patients to benefit from lab discoveries in epilepsy precision medicine. She worked as Associate Research Director at CURE Epilepsy helping to move funding forward for novel translational research in genomic medicine for patients with severe forms of pediatric-onset epilepsy. She then transitioned to the Director of Research and Strategy at the Lennox-Gastaut Syndrome (LGS) Foundation where she worked directly with patients to access precision therapies and partnered with researchers, clinicians, regulators, policymakers, therapy developers, and other advocacy groups to build a sustainable precision medicine infrastructure for all patients with epilepsy. Currently, Dr. Dixon- Salazar serves as the Executive Director of the LGS Foundation, where the mission is to improve the lives of individuals impacted by LGS through advancing research, awareness, education, and family support
In this CME Outfitters livestream symposium, expert faculty will instruct learners on the role of pro-inflammatory cytokines in the pathogenesis of IBD. Learners will be guided on the role of the IL-23/Th17 inflammatory axis in IBD pathogenesis and how to appraise the clinical implications of anti-IL-23 agents used in the treatment of IBD. Faculty will model the development of individualized treatment plans for patients with IBD that are eligible for treatment with an IL-23-targeted agent.
In this CME Outfitters livestream symposium, expert faculty will guide learners on identifying signs and symptoms of PBC, MASH, and MASLD, implementing evidence-based strategies for early and accurate diagnosis, implementing best practices for treatment, and applying multidisciplinary disease management to the care of patients.
In the first activity of this CME Outfitters BriefCase series, expert faculty will utilize a patient case format to illustrate utilization of current and emerging screening and diagnostic tools in diverse populations for early detection of AD, as well as integration of culturally sensitive patient and caregiver education strategies to improve SDM on brain health and AD management with patients.
