Posttest for Transfusion Therapy for Sickle Cell Disease Patients: Deep Dive into Red Blood Cell Exchange

Choose the correct statement regarding Sickle Cell Disease (SCD)*
- A. SCD is a recessive genetic blood disorder in which individuals inherit two copies of a mutated gene for hemoglobin production
- B. SCD is an autosomal dominant genetic blood disorder in which individuals inherit one copy of a mutated gene
- C. SCD is a recessive genetic blood disorder in which individuals inherit one copy of a mutated gene
- D. SCD is a recessive genetic blood disorder in which individuals inherit two copies of a mutated gene present in chromosome 1
Treatment for SCD is focused on*
- A. Pain management
- B. Pain management and treatment of the anemia
- C. Management of vaso-occlusive crisis and its consequences
- D. All of the above
Red Blood Cell Exchange (RBCX)*
- A. Is comparable to simple red blood cell transfusion
- B. Is an effective transfusion modality that is iron neutral
- C. Can treat the anemia and decrease levels of hemoglobin S without increasing iron load
- D. B and C
Choose the correct statement regarding Automated Red Blood Cell Exchange (RBCX)*
- A. Requires longer procedure time than manual exchange or simple transfusion
- B. Accurately predicts hematological targets more consistently than manual exchange, prevents volume overload and manages iron overload
- C. Increases blood viscosity and viscosity-related complications
- D. Leads to increased costs due to increase in hospital attendance in the medium to long term

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